trans-Nerolidol – Terpene Profile
Trans-Nerolidol is one of the two isomers that make up the Nerolidol sesquiterpene. This sesquiterpene is found in many aromatic herbs and plants, including ginger and jasmine, as well as in the essential oil neroli from which it takes its name. The terpene’s fresh, forest scents of rose and citrus are used in cosmetics and household products, and its fresh, earthy taste makes it a common flavoring ingredient. Trans-Nerolidol’s medicinal qualities are also well-documented. Recent research highlights Trans-Nerolidol’s success in combating parasite-borne diseases and parasites, fungal infections, and in aiding antibiotics against bacterial infections.
Medicinal qualities:
In vitro
Anti-fungal Anti-leishmanial
Antileishmanial Activity of the Terpene Nerolidol
Denise C. Arruda, Fabio Luiz D’Alexandri, Alejandro M. Katzin, Silvia R. B. Uliana (2005)
In vivo
Anti-leishmanial
Antifungal effect of eugenol and nerolidol against Microsporum gypseum in a guinea pig model.
Lee SJ, Han JI, Lee GS, Park MJ, Choi IG, Na KJ, Jeung EB.(2007)
Anti-Cancer
The effects of β-caryophyllene oxide and trans-nerolidol on the efficacy of doxorubicin in breast cancer cells and breast tumor-bearing mice.
Hanušová V, Caltová K, Svobodová H, Ambrož M, Skarka A, Murínová N, Králová V, Tomšík P, Skálová L. (2017)