Monoterpenes
Linalool – Terpene Profile
Linalool occurs in over 200 species of plants, commonly in lavender, rose and citrus. This terpene usually constitutes 5% or less of cannabis essential oil and has pleasant floral notes. Nevertheless, Linalool exhibits strong biological activity. Research studies showed that Linalool is one of the most powerful sedating terpene upon inhalation in mice.
Found in
Lavender
Boiling Point
198℃
388℉
Medicinal qualities:
In vivo
Anti-anxiety
Effects of inhaled Linalool in anxiety, social interaction and aggressive behavior in mice.
Linck, V. M., da Silva, A. L., Figueiró, M., Caramão, E. B., Moreno, P. R. H., & Elisabetsky, E. (2010)
Linalool Odor-Induced Anxiolytic Effects in Mice.
Harada, H., Kashiwadani, H., Kanmura, Y., & Kuwaki, T. (2018)
Reduces opioids dependency
Effect of linalool on morphine tolerance and dependence in mice.
Hosseinzadeh, H., Imenshahidi, M., Hosseini, M., & Razavi, B. M. (2012)
Analgesic
(-)-Linalool produces antinociception in two experimental models of pain.
Peana, A. T., D’Aquila, P. S., Chessa, M. L., Moretti, M. D., Serra, G., & Pippia, P. (2003)
Antidepressant
Antidepressant activity of Litsea glaucescens essential oil: identification of β-pinene and linalool as active principles.
Guzmán-Gutiérrez, S. L., Gómez-Cansino, R., García-Zebadúa, J. C., Jiménez-Pérez, N. C., & Reyes-Chilpa, R. (2012)
Sedative
Inhaled linalool-induced sedation in mice.
De Moura Linck, V., da Silva, A. L., Figueiró, M., Piato, Â. L., Herrmann, A. P., Dupont Birck, F., Caramão, E. B., Nunes, D. S., Moreno, P. R. H., & Elisabetsky, E. (2009)
Anti-inflammatory
Anti-inflammatory activity of linalool and linalyl acetate constituents of essential oils.
Peana, A. T., D’Aquila, P. S., Panin, F., Serra, G., Pippia, P., & Moretti, M. D. (2002)
In vivo & in vitro
Anti-convulsant
Anticonvulsant properties of linalool in glutamate-related seizure models.
Elisabetsky, E., Brum, L. F., & Souza, D. O. (1999)
High Linalool strain-specific terpene formulations:
50ml / 1.7oz$26200
250ml / 8.4oz$1,09100
Skin Repair
Enhancing Effect of Chiral Enhancer Linalool on Skin Permeation of Naproxen.
Guo X, Rong Y, Zhang L, Ye JC. (2016)
Linalool prevents oxidative stress activated protein kinases in single UVB-exposed human skin cells.
Gunaseelan S, Balupillai A, Govindasamy K, Ramasamy K, Muthusamy G, Shanmugam M1, Thangaiyan R, Robert BM, Prasad Nagarajan R1, Ponniresan VK, Rathinaraj P3. (2017)
Activities of ten essential oils towards Propionibacterium acnes and PC-3, A-549 and MCF-7 cancer cells.
Zu Y1, Yu H, Liang L, Fu Y, Efferth T, Liu X, Wu N. (2010)
Synergistic antifungal activity of tea tree (Melaleuca alternifolia) and lavender (Lavandula angustifolia) essential oils against dermatophyte infection
John P.Cassellaf Smith (2002)