Sesquiterpenes
Caryophyllene Oxide – Terpene Profile
Caryophyllene Oxide has a sweet, woody aroma and is mainly found in lemon balm and geranium. It is the product of the oxidation of Caryophyllene. Furthermore, it’s the component responsible for cannabis identification by drug-sniffing dogs. It is believed to be the only terpene in cannabis that has the ability to successfully bind with CB2 receptor. This unique skill makes it highly beneficial for medicinal uses, However, Caryophyllene Oxide only has a few known medical benefits.
Found in
Black Pepper
Boiling Point
279℃
534℉
Medicinal qualities:
In vivo
Analgesic & Anti-inflammatory
Analgesic and anti-inflammatory activity of Caryophyllene oxide from Annona squamosa L. bark
Chavana, M. J., Wakteb, P. S., & Shinde, D.B. (2010)
In vitro
Antimicrobial
Use of caryophyllene oxide as an antifungal agent in an in vitro experimental model of onychomycosis.
Yang, D., Michel, L., Chaumont, J. P., & Millet-Clerc, J. (1999)
Anti Tumor
β-Caryophyllene oxide inhibits growth and induces apoptosis through the suppression of PI3K/AKT/mTOR/S6K1 pathways and ROS-mediated MAPKs activation.
Park, K. R., Nam, D., Yun, H. M., Lee, S. G., Jang, H. J., Sethi, G., Cho, S. K., & Ahn, K. S. (2011)
High Caryophyllene Oxide strain-specific terpene formulations:
50ml / 1.7oz$24400
250ml / 8.4oz$1,01700