Alpha-Bisabolol – Profile
The primary source of this colorless sesquiterpene is German chamomile. Therefore it has a pleasant light floral odor and has been shown to have anti-nociceptive and anti-inflammatory activities. Furthermore, it has been shown to help improve sleep quality. Terpene α-Bisabolol is well suited for use in skin care products and can be useful in both sensitive skin and child/baby products as a soothing ingridient.
The Anticancer Effects of Novel α-Bisabolol Derivatives Against Pancreatic Cancer.
Murata Y, Kokuryo T, Yokoyama Y, Yamaguchi J, Miwa T, Shibuya M, Yamamoto Y, Nagino M. (2017)
BID and the α-bisabolol-triggered cell death program: converging on mitochondria and lysosomes.
Rigo A, Ferrarini I, Lorenzetto E, Darra E, Liparulo I, Bergamini C, Sissa C, Cavalieri E, Vinante F. (2019)
α-bisabolol enhances radiotherapy-induced apoptosis in endometrial cancer cells by reducing the effect of XIAP on inhibiting caspase-3.
Fang D, Wang H, Li M, Wei W. (2019)
(-)-α-Bisabolol attenuates visceral nociception and inflammation in mice.
Leite Gde, O., Leite, L. H., Sampaio Rde, S., Araruna, M. K., de Menezes, I. R., da Costa, J. G., & Campos, A. R. (2011)
Effect of (-)-α-Bisabolol on the Inflammatory Response in Systemic Infection Experimental Model in C57BL/6 Mice.
Cavalcante HAO, Silva-Filho SE, Wiirzler LAM, Cardia GFE, Uchida NS1, Silva-Comar FMS, Bersani-Amado CA1, Cuman RKN (2019)
The effects of chamomile extract on sleep quality among elderly people: A clinical trial.
Adib-Hajbaghery, M., & Nesa Mousavi, S. (2017)
Anti-nociceptive and anti-inflammatory activities of (−)-α-bisabolol in rodents.
Moura Rocha, N. F., Vasconcelos Rios, E. R., Rodrigues Carvalho, A. M., Cerqueira, G. S., de Araújo Lopes, A., Moreira Leal, L. K. A., Dias, M. L., de Sousa, D. P., & de Sousa, F. C. F. (2011)
Preparation of alpha-bisabolol and phenylethyl resorcinol/TiO2 hybrid composites for potential applications in cosmetics.
Leong HJ, Jang , Hyun KS, Jung SK2, Hong GH, Jeong HA, Oh SG. (2016)
High α-Bisabolol strain-specific terpene formulations:
While it proves to be a challenge for cultivation, this phenotype is considered to be one of the fullest and most desired aromatic profiles on the planet.